Pseudomonas aeruginosa Cell-to-Cell Signaling Is Required for Virulence in a Model of Acute Pulmonary Infection

Cell-to-cell signaling controls many virulence genes in Pseudomonas aeruginosa. We tested the virulence of las and rhl quorum-sensing mutants in neonatal mice. A lasI rhlI double mutant was nearly avirulent, and the respective single mutant strains were reduced in virulence compared with the wild-ty...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Pearson, James P., Feldman, Matthew, Iglewski, Barbara H., Prince, Alice
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2000
Assuntos:	Bacterial Infections
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC101761/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10858254/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.68.7.4331-4334.2000
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