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Linkage disequilibrium and recombination make a telomeric site for the Huntington's disease gene unlikely.
In a Scottish family in which Huntington's disease (HD) was segregating, recombination was observed between the D4S115/S111 and D4S43/S95 loci, with the HD gene associated with the more proximal D4S43/S95 locus. Analysis of linkage disequilibrium in Scottish families showed significant non-rand...
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| Publicado no: | J Med Genet |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMJ Publishing Group
1991
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC1016979/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1833548/ https://ncbi.nlm.nih.govhttps://doi.org/10.1136/jmg.28.8.520 |
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