Linkage disequilibrium and recombination make a telomeric site for the Huntington's disease gene unlikely.

In a Scottish family in which Huntington's disease (HD) was segregating, recombination was observed between the D4S115/S111 and D4S43/S95 loci, with the HD gene associated with the more proximal D4S43/S95 locus. Analysis of linkage disequilibrium in Scottish families showed significant non-rand...

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Bibliografiske detaljer
Main Authors: Barron, L, Curtis, A, Shrimpton, A E, Holloway, S, May, H, Snell, R G, Brock, D J
Format: Artigo
Sprog:Inglês
Udgivet: 1991
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1016979/
https://ncbi.nlm.nih.gov/pubmed/1833548
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