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A study of the Huntington's disease associated trinucleotide repeat in the Scottish population.

Accurate measurements of a specific CAG repeat sequence in the Huntington's disease (HD) gene in 337 HD patients and 229 normal controls from the Scottish population showed a range from 35 to 62 repeats in affected subjects and eight to 33 in normal subjects. A link between early onset of sympt...

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Опубликовано в: :J Med Genet
Главные авторы: Barron, L H, Warner, J P, Porteous, M, Holloway, S, Simpson, S, Davidson, R, Brock, D J
Формат: Artigo
Язык:Inglês
Опубликовано: BMJ Publishing Group 1993
Предметы:
Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC1016632/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8133495/
https://ncbi.nlm.nih.govhttps://doi.org/10.1136/jmg.30.12.1003
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