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Trinucleotide repeat length and progression of illness in Huntington's disease.

The genetic defect causing Huntington's disease (HD) has been identified as an unstable expansion of a trinucleotide (CAG) repeat sequence within the coding region of the IT15 gene on chromosome 4. In 50 patients with manifest HD who were evaluated prospectively and uniformly, we examined the r...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kieburtz, K, MacDonald, M, Shih, C, Feigin, A, Steinberg, K, Bordwell, K, Zimmerman, C, Srinidhi, J, Sotack, J, Gusella, J
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 1994
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1016662/
https://ncbi.nlm.nih.gov/pubmed/7853373
Tagiau: Ychwanegu Tag
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