Effect of Trinucleotide Repeats in the Huntington's Gene on Intelligence

BACKGROUND: Huntington's Disease (HD) is caused by an abnormality in the HTT gene. This gene includes trinucleotide repeats ranging from 10 to 35, and when expanded beyond 39, causes HD. We previously reported that CAG repeats in the normal range had a direct and beneficial effect on brain deve...

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Dettagli Bibliografici
Pubblicato in:EBioMedicine
Autori principali: Lee, Jessica K., Conrad, Amy, Epping, Eric, Mathews, Kathy, Magnotta, Vincent, Dawson, Jeffrey D., Nopoulos, Peg
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2018
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6013750/
https://ncbi.nlm.nih.gov/pubmed/29685790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2018.03.031
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