Effect of Trinucleotide Repeats in the Huntington's Gene on Intelligence

BACKGROUND: Huntington's Disease (HD) is caused by an abnormality in the HTT gene. This gene includes trinucleotide repeats ranging from 10 to 35, and when expanded beyond 39, causes HD. We previously reported that CAG repeats in the normal range had a direct and beneficial effect on brain deve...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Lee, Jessica K., Conrad, Amy, Epping, Eric, Mathews, Kathy, Magnotta, Vincent, Dawson, Jeffrey D., Nopoulos, Peg
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6013750/
https://ncbi.nlm.nih.gov/pubmed/29685790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2018.03.031
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