Gametic but not somatic instability of CAG repeat length in Huntington's disease.

Instability of a CAG repeat in 4p16.3 has been found in Huntington's disease (HD) chromosomes. Unlike a similar repeat in the fragile X syndrome, the expanded HD repeat showed no evidence of somatic instability in a comparison of blood, lymphoblast, and brain DNA from the same persons. Four pai...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:J Med Genet
Hauptverfasser: MacDonald, M E, Barnes, G, Srinidhi, J, Duyao, M P, Ambrose, C M, Myers, R H, Gray, J, Conneally, P M, Young, A, Penney, J
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMJ Publishing Group 1993
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC1016628/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8133508/
https://ncbi.nlm.nih.govhttps://doi.org/10.1136/jmg.30.12.982
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge