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PMS-601, a New Platelet-Activating Factor Receptor Antagonist That Inhibits Human Immunodeficiency Virus Replication and Potentiates Zidovudine Activity in Macrophages

We assessed the anti-human immunodeficiency virus (anti-HIV) activity in vitro of new platelet-activating factor (PAF) receptor antagonists, as PAF and viral replication are thought to be involved in HIV neuropathogenesis. We found that PMS-601 inhibited proinflammatory cytokine synthesis and HIV re...

Ausführliche Beschreibung

Gespeichert in:
Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Martin, M., Serradji, N., Dereuddre-Bosquet, N., Le Pavec, G., Fichet, G., Lamouri, A., Heymans, F., Godfroid, J. J., Clayette, P., Dormont, D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2000
Schlagworte:
Antiviral Agents
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC101619/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11036039/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.44.11.3150-3154.2000
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