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Genetic heterogeneity and mitochondrial DNA heteroplasmy in Leber's hereditary optic neuropathy.

Analysis of mitochondrial DNA from patients with Leber's hereditary optic neuropathy and their relatives showed that the previously reported mutation at base pair (bp) 11778, shown by loss of a recognition site for the restriction endonuclease SfaNI, was present in only four out of eight famili...

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Bibliografische gegevens
Hoofdauteurs: Holt, I J, Miller, D H, Harding, A E
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1989
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1015752/
https://ncbi.nlm.nih.gov/pubmed/2575667
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