Cytotoxic Necrotizing Factor Type 1 of Uropathogenic Escherichia coli Kills Cultured Human Uroepithelial 5637 Cells by an Apoptotic Mechanism

Pathogenic Escherichia coli associated with urinary tract infections (UTIs) in otherwise healthy individuals frequently produce cytotoxic necrotizing factor type 1 (CNF1), a member of the family of bacterial toxins that target the Rho family of small GTP-binding proteins. To gain insight into the fu...

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Main Authors: Mills, Melody, Meysick, Karen C., O'Brien, Alison D.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2000
Teme:
Molecular and Cellular Pathogenesis
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC101549/
https://ncbi.nlm.nih.gov/pubmed/10992497
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