Cytotoxic Necrotizing Factor from Escherichia coli Induces RhoA-Dependent Expression of the Cyclooxygenase-2 Gene

Cytotoxic necrotizing factor 1 (CNF) is a toxin produced by some isolates of Escherichia coli that cause extraintestinal infections. CNF can initiate signaling pathways that are mediated by the Rho family of small GTPases through a covalent modification that results in constitutive activation. In ad...

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Pubblicato in:	Infect Immun
Autori principali:	Thomas, Warren, Ascott, Zoe K., Harmey, Dympna, Slice, Lee W., Rozengurt, Enrique, Lax, Alistair J.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2001
Soggetti:	Molecular Pathogenesis
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC100062/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11598057/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.69.11.6839-6845.2001
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