Adjuvant Activity of Monophosphoryl Lipid A for Nasal and Oral Immunization with Soluble or Liposome-Associated Antigen

The effectiveness of monophosphoryl lipid A (MPL) as a mucosal adjuvant was investigated following oral or intranasal (i.n.) administration of an aqueous adjuvant formulation of MPL (MPL-AF) added to soluble antigen or liposomal antigen or incorporated into liposomal antigen membranes. Groups of BAL...

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Hlavní autoři: Childers, Noel K., Miller, Keri L., Tong, Giang, Llarena, Juan Carlos, Greenway, Terrance, Ulrich, J. Terry, Michalek, Suzanne M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2000
Témata:
Microbial Immunity and Vaccines
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC101499/
https://ncbi.nlm.nih.gov/pubmed/10992447
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