Adjuvant Activity of Monophosphoryl Lipid A for Nasal and Oral Immunization with Soluble or Liposome-Associated Antigen

The effectiveness of monophosphoryl lipid A (MPL) as a mucosal adjuvant was investigated following oral or intranasal (i.n.) administration of an aqueous adjuvant formulation of MPL (MPL-AF) added to soluble antigen or liposomal antigen or incorporated into liposomal antigen membranes. Groups of BAL...

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Veröffentlicht in:	Infect Immun
Hauptverfasser:	Childers, Noel K., Miller, Keri L., Tong, Giang, Llarena, Juan Carlos, Greenway, Terrance, Ulrich, J. Terry, Michalek, Suzanne M.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2000
Schlagworte:	Microbial Immunity and Vaccines
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC101499/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10992447/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.68.10.5509-5516.2000
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