Protective Immunity against Streptococcus mutans Infection in Mice after Intranasal Immunization with the Glucan-Binding Region of S. mutans Glucosyltransferase

Here we present the construction and characterization of a chimeric vaccine protein combining the glucan-binding domain (GLU) of the gtfB-encoded water-insoluble glucan-synthesizing glucosyltransferase enzyme (GTF-I) from Streptococcus mutans and thioredoxin from Escherichia coli, which increases th...

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Autors principals: Jespersgaard, Christina, Hajishengallis, George, Huang, Yan, Russell, Michael W., Smith, Daniel J., Michalek, Suzanne M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 1999
Matèries:
Microbial Immunity and Vaccines
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC97065/
https://ncbi.nlm.nih.gov/pubmed/10569773
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