Tripeptidyl Peptidase II Promotes Maturation of Caspase-1 in Shigella flexneri-Induced Macrophage Apoptosis

The invasive enteropathogenic bacterium Shigella flexneri activates apoptosis in macrophages. Shigella-induced apoptosis requires caspase-1. We demonstrate here that tripeptidyl peptidase II (TPPII), a cytoplasmic, high-molecular-weight protease, participates in the apoptotic pathway triggered by Sh...

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Hlavní autoři: Hilbi, Hubert, Puro, Robyn J., Zychlinsky, Arturo
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2000
Témata:
Molecular and Cellular Pathogenesis
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC101498/
https://ncbi.nlm.nih.gov/pubmed/10992446
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