Human Monocytes Kill Shigella flexneri but Then Die by Apoptosis Associated with Suppression of Proinflammatory Cytokine Production

Shigella flexneri infection of human macrophages is followed by rapid bacterial escape into the cytosol and secretion of IpaB, which activates caspase-1 to mediate cell death and release of mature interleukin (IL)-1β. Here we report a different outcome following infection of human peripheral blood m...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Hathaway, Lucy J., Griffin, George E., Sansonetti, Philippe J., Edgeworth, Jonathan D.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2002
Assuntos:	Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC128053/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12065527/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.70.7.3833-3842.2002
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