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Chemical incorporation of 1-methyladenosine into oligonucleotides

The base moiety of 1-N-methyladenosine can be protected with a chloroacetyl group for incorporation of this modified nucleoside into DNA and RNA. Carefully controlled anhydrous conditions are needed for deprotection of the oligonucleotides.

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Bibliografische gegevens
Gepubliceerd in:Nucleic Acids Res
Hoofdauteurs: Mikhailov, Sergey N., Rozenski, Jef, Efimtseva, Ekaterina V., Busson, Roger, Van Aerschot, Arthur, Herdewijn, Piet
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2002
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC101250/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11861902/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/30.5.1124
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