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Impaired activity of protease inhibitors towards neutrophil elastase bound to human articular cartilage.

OBJECTIVE: To investigate the effects of protease inhibitors on the ability of free and cartilage bound neutrophil elastase to degrade cartilage proteoglycan in vitro. METHODS: Cryostat sections of human articular cartilage were used as substrate, and proteoglycan loss induced by free or cartilage b...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kawabata, K, Moore, A R, Willoughby, D A
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1996
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1010146/
https://ncbi.nlm.nih.gov/pubmed/8733442
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