Destruction of articular cartilage by alpha(2) macroglobulin elastase complexes: role in rheumatoid arthritis

OBJECTIVE—Neutrophil elastase accounts for the ability of some fresh rheumatoid synovial fluids to degrade cartilage matrix in vitro. The aim of this study was to determine if enzyme activity could result from depletion of synovial fluid inhibitors or protection of the enzyme from inhibition.
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Detalhes bibliográficos
Main Authors: Moore, A., Appelboam, A., Kawabata, K., Da Silva, J. A P, D'Cruz, D., Gowland, G., Willoughby, D.
Formato: Artigo
Idioma:Inglês
Publicado em: 1999
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Extended Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1752824/
https://ncbi.nlm.nih.gov/pubmed/10343526
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