Role of TNF alpha in the induction of antigen induced arthritis in the rabbit and the anti-arthritic effect of species specific TNF alpha neutralising monoclonal antibodies.

OBJECTIVE--To investigate the role of tumour necrosis factor alpha (TNF alpha) in the development of antigen induced arthritis (AIA) in rabbits. METHODS--Monoclonal antibodies to rabbit TNF alpha were developed in rats and were used to detect TNF alpha in synovial fluid by enzyme linked immunosorben...

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Autors principals: Lewthwaite, J, Blake, S, Hardingham, T, Foulkes, R, Stephens, S, Chaplin, L, Emtage, S, Catterall, C, Short, S, Nesbitt, A
Format: Artigo
Idioma:Inglês
Publicat: 1995
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1005596/
https://ncbi.nlm.nih.gov/pubmed/7794042
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