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Generation and characterization of a neutralizing rat anti-rmTNF-alpha monoclonal antibody.

A rat anti-recombinant mouse tumour necrosis factor-alpha (rmTNF-alpha) monoclonal IgM antibody (1F3F3) with high specific binding activity for rmTNF-alpha was generated. The 1F3F3 monoclonal antibody (mAb) neutralizes the cytotoxic activity in vitro of rmTNF-alpha on L929 cells and inhibits the bin...

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Bibliografische gegevens
Hoofdauteurs: Lucas, R, Heirwegh, K, Neirynck, A, Remels, L, Van Heuverswyn, H, De Baetselier, P
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1990
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1384307/
https://ncbi.nlm.nih.gov/pubmed/2228022
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