Defective repair of O6-methylguanine-DNA in primary Sjögren's syndrome patients predisposed to lymphoma.

OBJECTIVE--To investigate a role for mutation in the aetiogenesis of autoimmune disease by examining levels of repairing enzyme for the promutagenic DNA base lesion, O6-methylguanine, in lymphocyte extracts from patients with autoimmune diseases. We included primary Sjögrens syndrome (PSS) patients...

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Detalhes bibliográficos
Main Authors: Guo, K, Major, G, Foster, H, Bassendine, M, Collier, J, Ross, D, Griffiths, I
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1005562/
https://ncbi.nlm.nih.gov/pubmed/7748022
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