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Normalization for cDNA microarray data: a robust composite method addressing single and multiple slide systematic variation

There are many sources of systematic variation in cDNA microarray experiments which affect the measured gene expression levels (e.g. differences in labeling efficiency between the two fluorescent dyes). The term normalization refers to the process of removing such variation. A constant adjustment is...

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Bibliografske podrobnosti
izdano v:Nucleic Acids Res
Principais autores: Yang, Yee Hwa, Dudoit, Sandrine, Luu, Percy, Lin, David M., Peng, Vivian, Ngai, John, Speed, Terence P.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2002
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC100354/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11842121/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/30.4.e15
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