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Normalization for cDNA microarray data: a robust composite method addressing single and multiple slide systematic variation

There are many sources of systematic variation in cDNA microarray experiments which affect the measured gene expression levels (e.g. differences in labeling efficiency between the two fluorescent dyes). The term normalization refers to the process of removing such variation. A constant adjustment is...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Autores principales: Yang, Yee Hwa, Dudoit, Sandrine, Luu, Percy, Lin, David M., Peng, Vivian, Ngai, John, Speed, Terence P.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2002
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC100354/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11842121/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/30.4.e15
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