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Normalization for cDNA microarray data: a robust composite method addressing single and multiple slide systematic variation

There are many sources of systematic variation in cDNA microarray experiments which affect the measured gene expression levels (e.g. differences in labeling efficiency between the two fluorescent dyes). The term normalization refers to the process of removing such variation. A constant adjustment is...

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Détails bibliographiques
Auteurs principaux: Yang, Yee Hwa, Dudoit, Sandrine, Luu, Percy, Lin, David M., Peng, Vivian, Ngai, John, Speed, Terence P.
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2002
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC100354/
https://ncbi.nlm.nih.gov/pubmed/11842121
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