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Natural and pharmacological regulation of telomerase

The extremities of eukaryotic chromosomes are called telomeres. They have a structure unlike the bulk of the chromosome, which allows the cell DNA repair machinery to distinguish them from ‘broken’ DNA ends. But these specialised structures present a problem when it comes to replicating the DNA. Ind...

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Detalhes bibliográficos
Main Authors: Mergny, Jean-Louis, Riou, Jean-François, Mailliet, Patrick, Teulade-Fichou, Marie-Paule, Gilson, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC100331/
https://ncbi.nlm.nih.gov/pubmed/11842096
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