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Natural and pharmacological regulation of telomerase

The extremities of eukaryotic chromosomes are called telomeres. They have a structure unlike the bulk of the chromosome, which allows the cell DNA repair machinery to distinguish them from ‘broken’ DNA ends. But these specialised structures present a problem when it comes to replicating the DNA. Ind...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Principais autores: Mergny, Jean-Louis, Riou, Jean-François, Mailliet, Patrick, Teulade-Fichou, Marie-Paule, Gilson, Eric
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2002
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC100331/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11842096/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/30.4.839
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