Imino proton NMR analysis of HDV ribozymes: nested double pseudoknot structure and Mg(2+) ion-binding site close to the catalytic core in solution

Minimized trans-acting HDV ribozyme systems consisting of three (Rz-3) and two (Rz-2) RNA strands were prepared and their folding conformations were analyzed by NMR spectroscopy. The guanosine residues in one of the enzyme components of Rz-3 were labeled with (13)C and (15)N. Imino proton signals we...

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izdano v:	Nucleic Acids Res
Principais autores:	Tanaka, Yoichiro, Hori, Tamaki, Tagaya, Mitsuhiro, Sakamoto, Taiichi, Kurihara, Yasuyuki, Katahira, Masato, Uesugi, Seiichi
Format:	Artigo
Jezik:	Inglês
Izdano:	Oxford University Press 2002
Teme:	Article
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC100292/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11809890/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/30.3.766
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