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Modeling RNA folding paths with pseudoknots: Application to hepatitis delta virus ribozyme

A quantitative understanding of nucleic acid hybridization is essential to many aspects of biotechnology, such as DNA microarrays, as well as to the structure and folding kinetics of RNA. However, predictions of nucleic acid secondary structures have long been impeded by the presence of helices inte...

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Detalhes bibliográficos
Main Authors: Isambert, Hervé, Siggia, Eric D.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC18642/
https://ncbi.nlm.nih.gov/pubmed/10823910
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