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An insight into the active site of a type I DNA topoisomerase from the kinetoplastid protozoan Leishmania donovani

DNA topoisomerases are ubiquitous enzymes that govern the topological interconversions of DNA thereby playing a key role in many aspects of nucleic acid metabolism. Recently determined crystal structures of topoisomerase fragments, representing nearly all the known subclasses, have been solved. The...

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Hlavní autoři: Das, Aditi, Mandal, Chhabinath, Dasgupta, Arindam, Sengupta, Tanushri, Majumder, Hemanta K.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2002
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC100284/
https://ncbi.nlm.nih.gov/pubmed/11809893
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