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Enhanced Gamma Interferon Production through Activation of Vα14(+) Natural Killer T Cells by α-Galactosylceramide in Interleukin-18-Deficient Mice with Systemic Cryptococcosis
We showed recently that activation of Vα14(+) natural killer T cells (NKT cells) by α-galactosylceramide (α-GalCer) resulted in increased gamma interferon (IFN-γ) production and host resistance to intravenous infection with Cryptococcus neoformans. In other studies, interleukin-18 (IL-18) activated...
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| Auteurs principaux: | , , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology
2001
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC100038/ https://ncbi.nlm.nih.gov/pubmed/11598033 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.11.6643-6650.2001 |
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