Activation of Natural Killer T Cells by α-Galactosylceramide Impairs DNA Vaccine-Induced Protective Immunity against Trypanosoma cruzi

Innate immunity as a first defense is indispensable for host survival against infectious agents. We examined the roles of natural killer (NK) T cells in defense against Trypanosoma cruzi infection. The T. cruzi parasitemia and survival of CD1d-deficient mice exhibited no differences compared to wild...

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Autores principales: Miyahira, Yasushi, Katae, Masaharu, Takeda, Kazuyoshi, Yagita, Hideo, Okumura, Ko, Kobayashi, Seiki, Takeuchi, Tsutomu, Kamiyama, Tsuneo, Fukuchi, Yoshinosuke, Aoki, Takashi
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2003
Materias:
Fungal and Parasitic Infections
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC148846/
https://ncbi.nlm.nih.gov/pubmed/12595437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.3.1234-1241.2003
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