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Interleukin-6- and Cyclic AMP-Mediated Signaling Potentiates Neuroendocrine Differentiation of LNCaP Prostate Tumor Cells

Neuroendocrine (NE) differentiation in prostatic adenocarcinomas has been reported to be an early marker for development of androgen independence. Secretion of mitogenic peptides from nondividing NE cells is thought to contribute to a more aggressive disease by promoting the proliferation of surroun...

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Autori principali: Deeble, Paul D., Murphy, Daniel J., Parsons, Sarah J., Cox, Michael E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC100010/
https://ncbi.nlm.nih.gov/pubmed/11713282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.24.8471-8482.2001
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