Interleukin-6- and Cyclic AMP-Mediated Signaling Potentiates Neuroendocrine Differentiation of LNCaP Prostate Tumor Cells

Neuroendocrine (NE) differentiation in prostatic adenocarcinomas has been reported to be an early marker for development of androgen independence. Secretion of mitogenic peptides from nondividing NE cells is thought to contribute to a more aggressive disease by promoting the proliferation of surroun...

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Bibliografiske detaljer
Main Authors: Deeble, Paul D., Murphy, Daniel J., Parsons, Sarah J., Cox, Michael E.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2001
Fag:
Cell Growth and Development
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC100010/
https://ncbi.nlm.nih.gov/pubmed/11713282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.24.8471-8482.2001
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