Interleukin-6- and Cyclic AMP-Mediated Signaling Potentiates Neuroendocrine Differentiation of LNCaP Prostate Tumor Cells

Neuroendocrine (NE) differentiation in prostatic adenocarcinomas has been reported to be an early marker for development of androgen independence. Secretion of mitogenic peptides from nondividing NE cells is thought to contribute to a more aggressive disease by promoting the proliferation of surroun...

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Detalhes bibliográficos
Main Authors: Deeble, Paul D., Murphy, Daniel J., Parsons, Sarah J., Cox, Michael E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC100010/
https://ncbi.nlm.nih.gov/pubmed/11713282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.24.8471-8482.2001
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