Interleukin-6- and Cyclic AMP-Mediated Signaling Potentiates Neuroendocrine Differentiation of LNCaP Prostate Tumor Cells

Neuroendocrine (NE) differentiation in prostatic adenocarcinomas has been reported to be an early marker for development of androgen independence. Secretion of mitogenic peptides from nondividing NE cells is thought to contribute to a more aggressive disease by promoting the proliferation of surroun...

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Hlavní autoři: Deeble, Paul D., Murphy, Daniel J., Parsons, Sarah J., Cox, Michael E.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2001
Témata:
Cell Growth and Development
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC100010/
https://ncbi.nlm.nih.gov/pubmed/11713282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.24.8471-8482.2001
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