Harnessing MerTK agonism for targeted therapeutics

Phagocytosis plays important roles both in homeostasis and under pathological conditions. Fcγ receptor-mediated phagocytosis has been exploited as an integral mechanism for antibody-based therapies. Unlike Fcγ receptor-mediated phagocytosis, MerTK-mediated phagocytic clearance is immunologically sil...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Vivekananda Kedage, Diego Ellerman, Yongmei Chen, Wei-Ching Liang, Joven Borneo, Yan Wu, Minhong Yan
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis Group 2020-01-01
Serier:mAbs
Fag:
Phagocytosis
bispecific antibody
immunologically silent
MerTK
Fcγ receptor
Online adgang:https://www.tandfonline.com/doi/10.1080/19420862.2019.1685832
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker