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Tyrosine Kinase Inhibitors as Reversal Agents for ABC Transporter Mediated Drug Resistance

Tyrosine kinases (TKs) play an important role in pathways that regulate cancer cell proliferation, apoptosis, angiogenesis and metastasis. Aberrant activity of TKs has been implicated in several types of cancers. In recent years, tyrosine kinase inhibitors (TKIs) have been developed to interfere wit...

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Main Authors: Nagaraju Anreddy, Pranav Gupta, Rishil J. Kathawala, Atish Patel, John N. D. Wurpel, Zhe-Sheng Chen
格式: Artigo
語言:Inglês
出版: MDPI AG 2014-09-01
叢編:Molecules
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在線閱讀:http://www.mdpi.com/1420-3049/19/9/13848
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