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Functional relevance of AcrB Trimerization in pump assembly and substrate binding.
AcrB is a multidrug transporter in the inner membrane of Escherichia coli. It is an obligate homotrimer and forms a tripartite efflux complex with AcrA and TolC. AcrB is the engine of the efflux machinery and determines substrate specificity. Active efflux depends on several functional features incl...
Shranjeno v:
| Main Authors: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Public Library of Science (PLoS)
2014-01-01
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| Serija: | PLoS ONE |
| Online dostop: | http://europepmc.org/articles/PMC3925222?pdf=render |
| Oznake: |
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