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Functional Relevance of AcrB Trimerization in Pump Assembly and Substrate Binding
AcrB is a multidrug transporter in the inner membrane of Escherichia coli. It is an obligate homotrimer and forms a tripartite efflux complex with AcrA and TolC. AcrB is the engine of the efflux machinery and determines substrate specificity. Active efflux depends on several functional features incl...
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| Asıl Yazarlar: | , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Public Library of Science
2014
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3925222/ https://ncbi.nlm.nih.gov/pubmed/24551234 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0089143 |
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