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Possible Role of Interaction between PPARα and Cyclophilin D in Cardioprotection of AMPK against In Vivo Ischemia-Reperfusion in Rats

Activated AMPK protects the heart from cardiac ischemia-reperfusion (IR) injury and is associated with inhibition of mitochondrial permeability transition pore (PTP) opening. On the other hand, pharmacological inhibition of the PTP reduces infarct size and improves cardiac function. However, it is u...

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Bibliografische gegevens
Hoofdauteurs: Giselle Barreto-Torres, Sabzali Javadov
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Hindawi Limited 2016-01-01
Reeks:PPAR Research
Online toegang:http://dx.doi.org/10.1155/2016/9282087
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