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Intrinsic disorder in protein interactions: insights from a comprehensive structural analysis.

We perform a large-scale study of intrinsically disordered regions in proteins and protein complexes using a non-redundant set of hundreds of different protein complexes. In accordance with the conventional view that folding and binding are coupled, in many of our cases the disorder-to-order transit...

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Detalles Bibliográficos
Main Authors: Jessica H Fong, Benjamin A Shoemaker, Sergiy O Garbuzynskiy, Michail Y Lobanov, Oxana V Galzitskaya, Anna R Panchenko
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science (PLoS) 2009-03-01
Series:PLoS Computational Biology
Acceso en liña:http://europepmc.org/articles/PMC2646137?pdf=render
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