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Intrinsic Disorder in Protein Interactions: Insights From a Comprehensive Structural Analysis

We perform a large-scale study of intrinsically disordered regions in proteins and protein complexes using a non-redundant set of hundreds of different protein complexes. In accordance with the conventional view that folding and binding are coupled, in many of our cases the disorder-to-order transit...

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Detalhes bibliográficos
Main Authors: Fong, Jessica H., Shoemaker, Benjamin A., Garbuzynskiy, Sergiy O., Lobanov, Michail Y., Galzitskaya, Oxana V., Panchenko, Anna R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2646137/
https://ncbi.nlm.nih.gov/pubmed/19282967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000316
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