HO-1 Contributes to Luteolin-Triggered Ferroptosis in Clear Cell Renal Cell Carcinoma via Increasing the Labile Iron Pool and Promoting Lipid Peroxidation

Ferroptosis, a novel form of regulated cell death characterized by disrupted iron metabolism and the accumulation of lipid peroxides, has exhibited enormous potential in the therapy of cancer particularly clear cell renal cell carcinoma (ccRCC). Luteolin (Lut), a natural flavonoid widely existing in...

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Päätekijät: Shangting Han, Fangyou Lin, Yucheng Qi, Cong Liu, Linxiang Zhou, Yuqi Xia, Kang Chen, Ji Xing, Zilin Liu, Weimin Yu, Yunlong Zhang, Xiangjun Zhou, Ting Rao, Fan Cheng
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Hindawi Limited 2022-01-01
Sarja:Oxidative Medicine and Cellular Longevity
Linkit:http://dx.doi.org/10.1155/2022/3846217
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