Neurophysiological effects of human-derived pathological tau conformers in the APPKM670/671NL.PS1/L166P amyloid mouse model of Alzheimer’s disease

Abstract Alzheimer’s Disease (AD) is a neurodegenerative disease characterized by two main pathological hallmarks: amyloid plaques and intracellular tau neurofibrillary tangles. However, a majority of studies focus on the individual pathologies and seldom on the interaction between the two pathologi...

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Main Authors: S. Tok, H. Maurin, C. Delay, D. Crauwels, N. V. Manyakov, W. Van Der Elst, D. Moechars, W. H. I. M. Drinkenburg
Format: Artigo
Jezik:Inglês
Izdano: Nature Portfolio 2022-05-01
Serija:Scientific Reports
Online dostop:https://doi.org/10.1038/s41598-022-11582-1
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