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A chemical analog of curcumin as an improved inhibitor of amyloid Abeta oligomerization.

Amyloid-like plaques are characteristic lesions defining the neuropathology of Alzheimer's disease (AD). The size and density of these plaques are closely associated with cognitive decline. To combat this disease, the few therapies that are available rely on drugs that increase neurotransmissio...

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Библиографические подробности
Главные авторы: Robert A Orlando, Amanda M Gonzales, Robert E Royer, Lorraine M Deck, David L Vander Jagt
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science (PLoS) 2012-01-01
Серии:PLoS ONE
Online-ссылка:http://europepmc.org/articles/PMC3307704?pdf=render
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