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A chemical analog of curcumin as an improved inhibitor of amyloid Abeta oligomerization.

Amyloid-like plaques are characteristic lesions defining the neuropathology of Alzheimer's disease (AD). The size and density of these plaques are closely associated with cognitive decline. To combat this disease, the few therapies that are available rely on drugs that increase neurotransmissio...

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Bibliografski detalji
Glavni autori: Robert A Orlando, Amanda M Gonzales, Robert E Royer, Lorraine M Deck, David L Vander Jagt
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science (PLoS) 2012-01-01
Serija:PLoS ONE
Online pristup:http://europepmc.org/articles/PMC3307704?pdf=render
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