Mechanisms of action of metformin in type 2 diabetes: Effects on mitochondria and leukocyte-endothelium interactions

Type 2 diabetes (T2D) is a very prevalent, multisystemic, chronic metabolic disorder closely related to atherosclerosis and cardiovascular diseases. It is characterised by mitochondrial dysfunction and the presence of oxidative stress. Metformin is one of the safest and most effective anti-hyperglyc...

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Detaylı Bibliyografya
Asıl Yazarlar: Nadezda Apostolova, Francesca Iannantuoni, Aleksandra Gruevska, Jordi Muntane, Milagros Rocha, Victor M. Victor
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2020-07-01
Seri Bilgileri:Redox Biology
Konular:
Type 2 diabetes
Metformin
Oxidative stress
Pathophysiology
Treatment
Atherosclerosis
Online Erişim:http://www.sciencedirect.com/science/article/pii/S2213231719315393
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