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Mechanisms of action of metformin in type 2 diabetes: Effects on mitochondria and leukocyte-endothelium interactions

Type 2 diabetes (T2D) is a very prevalent, multisystemic, chronic metabolic disorder closely related to atherosclerosis and cardiovascular diseases. It is characterised by mitochondrial dysfunction and the presence of oxidative stress. Metformin is one of the safest and most effective anti-hyperglyc...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Apostolova, Nadezda, Iannantuoni, Francesca, Gruevska, Aleksandra, Muntane, Jordi, Rocha, Milagros, Victor, Victor M.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7296337/
https://ncbi.nlm.nih.gov/pubmed/32535544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2020.101517
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