טוען...
A Paired RNAi and RabGAP Overexpression Screen Identifies Rab11 as a Regulator of β-Amyloid Production
Alzheimer’s disease (AD) is characterized by cerebral deposition of β-amyloid (Aβ) peptides, which are generated from amyloid precursor protein (APP) by β- and γ-secretases. APP and the secretases are membrane associated, but whether membrane trafficking controls Aβ levels is unclear. Here, we perfo...
שמור ב:
Main Authors: | , , , , , , , , , , , , , , , |
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פורמט: | Artigo |
שפה: | Inglês |
יצא לאור: |
Elsevier
2013-12-01
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סדרה: | Cell Reports |
גישה מקוונת: | http://www.sciencedirect.com/science/article/pii/S2211124713007353 |
תגים: |
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